A label free method to look at molecules down to sizes of 3 nm radius
Nanofluidic scattering microscopy
An optical microscopy technique that enables direct label-free imaging of freely moving biomolecules in real-time.
Resolution is high enough to capture the Brownian motion of a biomolecule with molecular weight ranging down to tens of kDa.
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Determine both mass and size of single molecules
Measure the hydrodynamic radius of single nanoparticles while they are moving freely in their natural liquid environment.
At the same time, measure the mass and the optical contrast.
A simple procedure with an advanced technology
It is easy to use, all that is needed is a droplet of your sample.
How does it work?
Envues technology consists of three core elements. Together they create a powerful technique that allows you to study extremely small particles in a completly new way.
1. The nanofluidic chip
A chip fabricated in a cleanroom facility comprising nanofluidic channels through which the biomolecules flow and diffuse.
2. The microscope
The nanofluidic channels are imaged by a dark-field optical microscope that was specially designed to maintain a high mechanical stability and to maximize the imaging quality.
3. Data analysis
We use a combination of machine learning and conventional algorithms to extract as much information as possible from the data.